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diagnosis algorithm lymphocytic anemia aplastic causes classification disorders hemeonc hodgkins lymphoma markers mds myelodysplasia myelodysplastic neutrophil pathophysiology scleroderma syndromes thrombocytosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Artifact (redo CBC ... Myelogenous Leukemia ... effect following treatment ... following EtOH induced thrombocytopenia ... Algorithm #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... Neutrophils • Immature/Myeloblasts ... - infiltrates (anemia ... , thrombocytopenia ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... , thrombocytopenia ... microglobulin Treatment ... #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... Vmphocytosis on routine CBC ... #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... - CD7, CD3 Chronic ... • Lymphoid (CLL ... ↑ WBC ... #Disorders #hematology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
of peripheral blood ... on the left Myeloblast ... Tissue damage • Leukemia ... #differential # ... #CBC #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
cell count (anemia ... Marrow Failure • Chronic ... count with differential ... Syndromes #diagnosis #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
virus (EBV) • Leukemia ... Treatment: ... result from low blood ... #oncology #hematology ... #diagnosis #management
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
the mainstay of treatment ... frequent in men Chronic ... be seen after blood ... #Diagnosis #comparison ... #table #dermatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
platelets - WBC ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
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