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diagnosis hematology clinical blood differential bloodsmear path algorithm hemolytic microscopy workup causes oncology pathology peripheral leukemia macrocytosis management testing auer
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... eosinophilia, basophilia ... Neutrophils • Immature/Myeloblasts ... - infiltrates (anemia ... • Peripheral smear
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood Smear ... Megaloblastic Anemia ... Autoimmune hemolytic anemia ... , Thalassemia Basophilic ... Peripheral #Blood #Smear
Comparison of basophils and mast cells (in bone marrow). #Basophils #MastCells #Pathology #Marrow #Smear #Microscopy #Comparison #Table
Comparison of basophils ... #Basophils #MastCells ... Pathology #Marrow #Smear
Megaloblastic Anemia vs Normal Peripheral Smear #Megaloblastic #Anemia #Peripheral #Smear #Comparison #Clinical #Hypersegmented #Neutrophil
Megaloblastic Anemia ... Normal Peripheral Smear ... Megaloblastic #Anemia ... #Peripheral #Smear
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Algorithm Signs of anemia ... Abnormal peripheral smear ... Autoimmune Hemolytic Anemias ... #Hemolytic #Anemias
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA Warm AIHA: - 70%; IgG mediated -
Autoimmune Hemolytic Anemia ... or negative - Smear ... C3 positive - Smear ... Autoimmune #Hemolytic #Anemia
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
large, immature myeloblasts ... BloodSmear #Blood #Smear
Dacrocytes (tear drop cells) Other poikilocytes resemble a pear or teardrop. The narrow, tapered end may be
metaplasia, pernicious anemia ... some hemolytic anemias ... BloodSmear #Blood #Smear
Laboratory Testing in Hemolytic Anemia Intravascular vs Extravascular Hemolysis Reticulocytes Unconjugated bilirubin LDH Peripheral smear Haptoglobin Urine hemosiderin Urine hemoglobin Carboxyhemoglobin #Hemolytic #Anemia #Laboratory #Testing #workup
Testing in Hemolytic Anemia ... LDH Peripheral smear ... #Hemolytic #Anemia
Elliptocyte - Note the shape of these appropriately named erythrocytes. In addition to hereditary elliptocytosis, elliptocytes can
megaloblastic anemia ... myelophthisic anemia ... sideroblastic anemia ... iron deficiency anemia ... BloodSmear #Blood #Smear
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