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diagnosis management hematology differential oncology leukemia syndrome chronic cll neurology nutrition rheumatology abscess acute algorithm anemia aplastic ascorbicacid b12 bands
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Vmphocytosis on routine CBC ... 5) Symptoms of anemia ... transformation) Treatment ... Indications for Treatment ... AIHA, PRCA) • Treatment
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Lymphocytosis on CBC ... surface molecules: CD5 ... • Neutropenia, anemia ... microglobulin Treatment
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemia): • Lymphocytes ... -> AML: Blast crises ... eosinophilia, basophilia ... Neutrophils • Immature/Myeloblasts ... - infiltrates (anemia
Causes of Aplastic Anemia #Aplastic #Anemia #Causes #Pathophysiology #Pathology #Treatment #Management #Differential
Causes of Aplastic ... Anemia #Aplastic ... #Anemia #Causes ... #Pathophysiology ... #Pathology #Treatment
Evaluation of Leukocytosis: The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages. Include
cells within the myeloblast ... eosinophils, & basophils ... , monocytes, & lymphocytes ... the underlying cause ... NEUTROPHILS #WCC #BASOPHILS
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview ... on the left Myeloblast ... Degree of bandemia ... neutrophil #WBC #CBC ... #hematology #pathophysiology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Artifact (redo CBC ... effect following treatment ... Iron deficiency anemia ... Diagnosis #Algorithm #Causes
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
reticularis Blood: Anemia ... • Lymphocytic infiltration ... xeropthalmia) Mouth: • Lymphocytic ... inflammation tends to cause ... RheumatoidArthritis #RA #pathophysiology
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
14%), in which case ... • Leukocyte-lymphocyte ... enzymes ↑ • Mild anemia ... Photophobia • Lymphocytic ... antibody test) Treatment
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
• Most common cause ... Lung Abscess Pathophysiology ... Diagnosis: • CBC ... Leukocytosis, anemia ... #differential #causes
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