13 results
diagnosis hematology management differential oncology leukemia chronic syndrome workup abscess acute cbc cd4 classification common cvid disorders hemeonc hemophagocytic hlh
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... eosinophilia, basophilia ... Neutrophils • Immature/Myeloblasts ... - infiltrates (anemia ... #Leukemia #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... surface molecules: CD5 ... • Neutropenia, anemia ... microglobulin Treatment ... workup #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... Vmphocytosis on routine CBC ... transformation) Treatment ... uw_IMresidency #CLL ... Leukemia #oncology #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
decreased PLT count: CBC ... peripheral blood smear, HIV ... changes), high MCV anemia ... not required in all ... #Workup #hematology
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
+ T-cell count can ... • Leukocyte-lymphocyte ... enzymes ↑ • Mild anemia ... Photophobia • Lymphocytic ... antibody test) Treatment
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Left Shift: • Cell ... precursors" • Stab cell ... on the left Myeloblast ... neutrophil #WBC #CBC ... #hematology #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Drugs, Unknown cause ... Treatment: • ... #summary #rheumatology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
T-cell count of ... mL or 20% total lymphocyte ... • Infections - HIV ... ICL #diagnosis #hematology ... #Differential #Causes
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
• Most common cause ... Lung Abscess Pathophysiology ... Diagnosis: • CBC ... Leukocytosis, anemia ... #differential #causes
Visceral Leishmaniasis - Diagnosis and Management Summary Species: Leishmania donovani, Leishmania infantum, Leishmania chagasi Where: South Asia, East
Evades innate and cell-mediated ... antigen-specific CD4 ... Weight Loss • Can cause ... Lymphohistiocytosis • Anemia ... stibogluconate 20 mg/kg/d IV
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