36 results
Elliptocyte - 
Note the shape of these appropriately named erythrocytes.
In addition to hereditary elliptocytosis, elliptocytes can
megaloblastic anemia ... myelophthisic anemia ... sideroblastic anemia ... Clinical #Path #BloodSmear ... #Blood #Smear #
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
large, immature myeloblasts ... Clinical #Path #BloodSmear ... #Blood #Smear #
Dacrocytes (tear drop cells) 
Other poikilocytes resemble a pear or teardrop. The narrow, tapered end
may be
metaplasia, pernicious anemia ... some hemolytic anemias ... Clinical #Path #BloodSmear ... #Blood #Smear #
Here is another peripheral blood smear demonstrating changes with iron deficiency anemia. Note the increased zone
peripheral blood smear ... iron deficiency anemia ... PeripheralBloodSmear #BloodSmear ... #Anemia #IronDeficiency
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... - Differential Diagnosis ... Algorithm Signs of anemia ... Abnormal peripheral smear ... #Differential #Diagnosis
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
with hemolytic anemias ... Clinical #Path #BloodSmear ... #Blood #Smear #
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
Autoimmune Hemolytic Anemia ... or negative - Smear ... C3 positive - Smear ... Autoimmune #Hemolytic #Anemia ... Pathophysiology #diagnosis
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Testing in Hemolytic Anemia ... LDH Peripheral smear ... #Hemolytic #Anemia ... Testing #workup #diagnosis
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... - Differential Diagnosis ... Normochromic RBCs on Smear ... Spherocytes on Smear ... #Differential #Diagnosis
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic anemia ... and laboratory diagnosis ... Microangiopathic hemolytic anemia ... arrow) Peripheral smear ... Hematology #Pathology #Smear