13 results
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... - Differential Diagnosis ... Normal Blood Smear ... #Differential #Diagnosis ... #Algorithm #Causes
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
ordering a peripheral smear ... patients with macrocytosis ... the most likely cause ... recovery also causes ... #Diagnosis #Macrocytosis
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Hemolytic Anemia 1) DIAGNOSE ... C3d • Blood smear ... 2) LOOK FOR a cause ... Hemolytic #Anemia #diagnosis ... #management #treatment
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
She was diagnosed ... hospitalization and treatment ... peripheral blood smear ... Clinical #Path #BloodSmear ... #Blood #Smear #
Borrelia recurrentis on Peripheral Blood Smear
23M Somali refugee recently arrived w/severe abd pain, confusion and fever
LBRF can be diagnosed ... can be used for diagnosis ... Treatment is tetracycline ... initiation of treatment ... #recurrentis #BloodSmear
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Peripheral smear ... + Bleeding Treatment ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... -> AML: Blast crises ... Neutrophils • Immature/Myeloblasts ... • Peripheral smear ... Hematology #Oncology #Diagnosis
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Hematologic disease caused ... Nodular → Mular DIAGNOSIS ... phase: Peripheral smear ... TREATMENT: ​• Acute ... #Oroya #Fever #diagnosis
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
Trypanosomiasis - Diagnosis ... infectious disease caused ... positive serology, smear ... thick peripheral smears ... Trypanosomiasis #Diagnosis
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... hypersegmented neutrophils, macrocytosis ... Check for IF ab Treatment ... consider other diagnosis ... Cobalamin #Deficiency #diagnosis