8 results
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Cirrhosis (PBC) ... - Summary PBC ... #PBC #cholangitis ... #diagnosis #workup ... #hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Cirrhosis - Diagnosis ... consistent with PBC ... #PBC #Primary ... #Diagnosis #Algorithm ... #hepatology
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
Algorithm • 12 ... : CBC with diff, ... reticulocyte count, LFTs ... ↑ Destruction (hemolysis ... #Algorithm #hematology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Ducts - PBC ... Congenital, Others, Cirrhosis ... Burak @kwburak #LFTs ... #diagnosis #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Autoimmune hepatitis, PBC ... stone, Malignancy, PBC ... hepatitis: < 1 • Cirrhosis ... • LDH: Heart, RBC ... #algorithm #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Algorithm ALP ... - Drugs - Primary ... biliary Cholangitis ... (PBC) - Other ... #Algorithm #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
• Bilirubin: RBC ... cardiac muscle, RBC ... • LDH: Heart, RBC ... #diagnosis #differential ... #Hepatology #transaminitis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
decreased PLT count: CBC ... gastric bypass), LFT ... , HBsAg/anti-HBc ... unclear, or if a primary ... #hematology