15 results
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
↑ LDH • Anti-RBC ... • Blood smear: Differential ... 2) LOOK FOR a cause ... Anemia #diagnosis #management ... #treatment #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... or if a primary hematologic ... Platelet #Disorders #Differential ... #Workup #hematology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
on the left Myeloblast ... Neutrophil (Normal) Differential ... Corticosteroid use • Autoimmune ... #Bandemia #differential ... #CBC #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... Intravascular Hemolysis - Differential ... Cold AIHA • Alloimmune ... elliptocytosis - RBC ... #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... elliptocytosis, autoimmune ... Hemolytic #Anemia #Differential ... Diagnosis #Algorithm #workup ... #hematology #testing
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... • Intrinsic RBC ... Extravascular #Causes ... #differential # ... diagnosis #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Pain - Arthritis Differential ... , erythema and WBC ... effusion with few WBCs ... weeks) Can Be Caused ... Diagnosis #MSK #rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
lower limbs) • WBC ... Like in this case ... Joint #Pain #MSK #rheumatology ... #approach #workup ... #differential #
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
decrease in most cases ... from ischemia WBC ... count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... an underlying cause ... Better call hematology ... else is driving RBC ... #hematology