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diagnosis pbc algorithm cirrhosis anemia differential hemolytic agglutinin causes cholangitis classification cold disease extravascular hepatitis hodgkins injury intravascular liver lymphoma
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Immune-mediated: - Autoimmune ... idiopathic) - Autoimmune ... usually IgM) (e.g. primary ... • Intrinsic RBC ... differential #diagnosis #hematology
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... of associated autoimmune ... #PBC #Primary ... #Biliary #Cirrhosis ... Diagnosis #Algorithm #hepatology
Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
Primary Biliary ... family history of autoimmune ... cell mediated autoimmune ... #Primary #Biliary ... Pathophysiology #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Celiac disease • Autoimmune ... : Autoimmune hepatitis ... Extrahepatic - Biliary ... (hemolysis) • ... diagnosis #algorithm #hepatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
15% of AIHA Primary ... Viral infection, autoimmune ... Blood smear - RBC ... CLL (older) • Autoimmune ... #anemia #hematology
Proposed Schema for the Management of Pruritus in Primary Biliary Cholangitis (PBC). Cholestyramine up to 4g
Schema for the Management ... of Pruritus in Primary ... Biliary Cholangitis ... #PBC #Management ... #Hepatology #Algorithm
Primary Biliary Cirrhosis - Management A. Initiate therapy - Initiate 1st line therapy with UDCA (13-15
Primary Biliary ... Cirrhosis - Management ... survey disease #PBC ... #Primary #Biliary ... #Treatment #hepatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunosuppression • Autoimmune ... nodosum • Immune hemolytic ... platelets - WBC ... classification #hematology ... #oncology #management
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