18 results
diagnosis algorithm differential causes cirrhosis pbc injury liver acute anemia cholangitis hemolytic rheumatology agglutinin aih antibodies associations autoantibodies classification cold
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
- Acute biliary ... - Autoimmune ... Hemochromatosis - Primary ... biliary cholangitis ... #Differential #Hepatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Malignant • Primary ... • Autoimmune ... Cholangitis • Primary ... Biliary Cirrhosis ... Algorithm #Causes #Hepatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Immune-mediated: - Autoimmune ... idiopathic) - Autoimmune ... usually IgM) (e.g. primary ... • Intrinsic RBC ... differential #diagnosis #hematology
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... of associated autoimmune ... #PBC #Primary ... #Biliary #Cirrhosis ... Diagnosis #Algorithm #hepatology
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Inflammation - Hepatitis ... Schistosomiasis - Autoimmune ... congenital - Primary ... biliary cirrhosis ... #Differential #Hepatology
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 Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
Primary Biliary ... family history of autoimmune ... cell mediated autoimmune ... #Primary #Biliary ... Pathophysiology #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Celiac disease • Autoimmune ... : Autoimmune hepatitis ... Extrahepatic - Biliary ... (hemolysis) • ... diagnosis #algorithm #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Other: NAFLD, Autoimmune ... biliary obstruction ... Malignancy, 1° PBC ... Extrahepatic • Biliary ... Acute #algorithm #hepatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
common in SLE, autoimmune ... hepatitis Anti-CCP ... , Anti-gp210 - Primary ... biliary cirrhosis ... (PBC) Anticentromere
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
biliary cholangitis ... , Primary sclerosing ... steatosis • Autoimmune ... hepatitis #DILI ... Diagnosis #Algorithm #hepatology
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