69 results
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
cells within the myeloblast ... Mature WBC: 80- ... LEUCOCYTOSIS WBC ... ) and immature WBCs ... the underlying cause
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... - Low Serum B12 ... - Low Serum B12 ... Cells, Normal WBCs ... Diagnosis #Algorithm #Causes
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
on the left Myeloblast ... Even with normal WBC ... article/S0002-9343(12 ... relative to both WBC ... 21% had normal WBC
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
(RBC = red blood ... and a vitamin B12 ... the most likely cause ... recovery also causes ... that occur with B12
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
RBCs Decreased RBC ... Deficiency • B12 ... Thalassemia • RBC ... Disorder • RBC ... Diagnosis #Algorithm #Causes
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
Causes of False ... == Decreased RBC ... turnover • Iron, B-12 ... Glucose Content • RBC ... Reduction == Increase RBC
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... Artifact (redo CBC ... effect following treatment ... Diagnosis #Algorithm #Causes
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
are caused by prerenal ... creatinine (in 12 ... CONSIDER INTRINSIC CAUSES ... microscopy for WBCs ... , RBCs, casts, crystals
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
Vitamin B12 (Cobalamin ... Etiology: • Vit B12 ... • Common Causes ... • Labs: - CBC ... Check for IF ab Treatment
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... count cause hyperviscosity ... • Lab values: WBC ... organ damage • Treatment ... Low calcium • Treatment