20 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Workup History ... procedures - Infection ... decreased PLT count: CBC ... test, ANA (e.g., SLE ... (CVID, WAS), (neurologic
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Cerebrovascular Disease ... APS), Secondary prevention ... #CNS #neurology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... weeks without infection ... Lymphocytosis on CBC ... #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... involvement • 30%: CNS ... Neutrophils • Immature/Myeloblasts ... #Leukemia #Hematology ... #Oncology #Diagnosis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... (CAS): - Due ... , autoimmune disorder ... Blood smear - RBC ... hemolytic #anemia #hematology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
CNS Infection in ... - Differential Diagnosis ... Antimicrobial treatment ... Suspect in movement disorders ... Demyelinating disease
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Consider sickle cell ... inclusions - If infection ... membrane disorder ... #Algorithm #workup ... #hematology #testing
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... fibromyalgia) • Infections ... Malignancy (e.g. hematologic ... and CNS • Headache ... titers > 1:80 • CBC
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
leukemia in adults • Disorder ... Vmphocytosis on routine CBC ... Complications: 1) Infection ... chemotherapy for low-risk disease ... Leukemia #oncology #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Rare Disorder: ... - CBC may also ... Treatment: - Systemic ... #diagnosis #dermatology