12 results
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... , Auer rod • Lymphoid ... bcr-able (+) ↑ WBC ... @AmyChung #Blood ... #Disorders #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphocytosis on CBC ... can indicate disease ... lymphoproliferative disorders ... microglobulin Treatment ... #hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... Bite Cell RBC: G6PD ... Unstable hemoglobin disorders ... Target Cell RBC ... differential #diagnosis #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
leukemia in adults • Disorder ... Vmphocytosis on routine CBC ... lymphoma (Richter ... chemotherapy for low-risk disease ... #hematology #hemeonc
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
of peripheral blood ... Left Shift: • Cell ... on the left Myeloblast ... • Autoimmune diseases ... #CBC #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... extramedullary disease ... Neutrophils • Immature/Myeloblasts ... - infiltrates (anemia ... #Hematology #Oncology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
or lymphoid malignancy ... - Lymphoid Malignancy ... malignancies - B-cell ... sensitize red blood ... #hematology #diagnosis
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... number of sites of disease ... Treatment • Early ... classification #hematology ... #oncology #management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... Myeloproliferative Disease ... Neutropenia • Platelet Disorders ... Syndromes #diagnosis #hematology ... #oncology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Angioimmunoblastic T-cell ... lymphoma • Evans ... titers > 1:80 • CBC ... : • Chronic B-cell ... Erythematosus #Diagnosis #Rheumatology