14 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... Fever, Arthralgia/arthritis ... fraction < 20% Differential ... #diagnosis #management ... #treatment #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Cerebrovascular Disease ... autoantibodies that will cause ... #management #treatment
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... ) Differential Diagnosis ... , AS Treatment: ... #diagnosis #management ... #signs #symptoms
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Classified among the secondary ... idiopathic arthritis ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
thought to be secondary ... carotid sinus syndrome ... further guide management ... orthostatic vital sign ... The treatment strategy
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
tests algorithm ... symptoms/signs ... presence of metabolic syndrome ... #Algorithm #Hepatology ... Liver #Enzymes #Differential
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... signs/sx of inflammation ... very remarkable w/differential ... Treatment of GCA ... #Management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis: • Systemic ... purpura: Strong sign ... fluid (CSF) is abnormal ... tract, and often causes ... #Diagnosis #Rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
processes: • Systemic ... cryoglobulins • Negative causes ... to medium-sized arteries ... Antiphospholipid syndrome ... hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... to 8 years Clinical ... hemolytic anemia) • Systemic ... DDX - Other causes ... #diagnosis #management