10 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... Neutrophils • Immature/Myeloblasts ... - infiltrates (anemia ... bone marrow and secondary ... #Hematology #Oncology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic ... AnemiaToxic ... Leukemia, Tumour ... Non-lmmune: • HELLP Syndrome ... #Causes #Hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... virus (EBV) • Leukemia ... anemia Treatment ... #Anemia #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... dys- (abnormal) -plastic ... cytopenias (usually anemia ... transformation to acute leukemia ... #hematology #oncology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
malignancies • Anemia ... Myelodysplastic syndrome ... myeloid leukemia ... (CML) - Dr. ... #secondary
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
(dry skin) • Atopic ... Creatinine & BUN: • Chronic ... • Lymphoma • Leukemia ... Myelodisplastic syndrome ... #generalized #dermatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... • Neutropenia, anemia ... Pure red cell aplasia ... microglobulin Treatment ... diagnosis #workup #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... • Aplastic Anemia ... Marrow Failure • Chronic ... Cell Leukemia ... #oncology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Creatinine & BUN: • Chronic ... • Lymphoma • Leukemia ... Myelodisplastic syndrome ... #Pruritus #secondary ... #generalized #dermatology
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
algorithm 2018. ... acute myeloid leukemia ... (AML). ... disease tolerate anemia ... #algorithm #hematology