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oncology comparison erythematosus immunology lupus lymphocytic lymphomas lymphoproliferative mds myelodysplasia myelodysplastic nonhodgkin pathergy pathophysiology rheumatology scleroderma sle syndromes table workup
Eosinophilia - Differential Diagnosis Algorithm Idiopathic Eosinophilia Primary Eosinophilia: • Primary hypereosinophilic syndrome • Eosinophilic Leukemia • MPN/MDS
Eosinophilia - Differential ... Diagnosis Algorithm ... Secondary Eosinophilia ... , CML, T-cell leuk ... Diagnosis #Algorithm
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... extramedullary disease ... -> Invade Skin: ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... cells can indicate disease ... microglobulin Treatment ... #Leukemia #diagnosis ... workup #oncology #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... lymphadenopathy more diffuse ... Treated Like Acute Leukemias ... #Classification ... pathophysiology #Hematology
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
Diagnosis Eosinophilic ... the mainstay of treatment ... Nephrogenic Systemic ... Fibrosis: - Secondary ... #table #dermatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Disease Classification ... permanent alopecia Differential ... with Lupus: • Chronic ... Hodgkin lymphoma and leukemia
Pathergy Summary Overview What is pathergy? Pathergy is an exaggerated skin injury occurring after minor trauma such as
myeloid leukemia ... (CML) treated with ... #differential # ... allergy #immunology ... #dermatology #skin
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... DDX: Rule Out Secondary ... Marrow Failure • Chronic ... (CML) • Felty ... #hematology #oncology
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