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oncology algorithm antinxp2 antinxp2dm bandemia basophils cbc dermatologic dermatomyositis gpa granulomatosis management mds myelodysplasia myelodysplastic neutrophil pathophysiology polyangiitis syndromes thrombocytopenia
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... Diagnosis Framework ... #Differential # ... Diagnosis #causes ... #hematology #basophils
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
- Differential ... Megakaryopoiesis • Aplastic ... Leukemia, Tumour ... ITP • SLE • CLL ... #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... eosinophilia, basophilia ... Neutrophils • Immature/Myeloblasts ... #Hematology #Oncology ... #Diagnosis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... Polyangiitis #GPA #dermatology ... #rash #diagnosis ... #rheumatology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... on the left Myeloblast ... Tissue damage • Leukemia ... #Bandemia #differential ... #WBC #CBC #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Anemia • Aplastic ... Leukemia • Idiopathic ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... auricular papules Clinical ... Muscle atrophy may cause ... #management #rheumatology ... #dermatology
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