51 results
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
(MM, Lymphoma, Leukemia ... ) • GI diseases ... Corticosteroid use • Primary ... #Osteoporosis #pathophysiology ... #signs #symptoms
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... extramedullary disease ... Neutrophils • Immature/Myeloblasts ... + distinctive primary ... #Hematology #Oncology
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Plasma cell leukemia ... Aggressive disease ... over-represented in primary ... plasma cell leukemia ... Clinical #Smear #Hematology
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis

#pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver Disease ... : Primary Biliary ... Cirrhosis vs Primary ... Cholangitis #pathophysiology ... #pbc #psc #hepatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Chronic Myelogenous Leukemia ... • Primary Myelofibrosis ... disorders • Celiac disease ... Non malignant hematologic ... states • Non-hematologic
Manifestations of IgG4-related disease by organ system.
 The most common primary disease features are indicated in
of IgG4-related disease ... The most common primary ... disease features ... Systems #Diagnosis #Hematology ... #Signs #Symptoms
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Malignant • Primary ... • Lymphoma • Leukemia ... Hemochromatosis • Wilson's Disease ... Cholangitis • Primary ... Algorithm #Causes #Hepatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Causes == Primary ... Cholestatic liver disease ... • Lymphoma • Leukemia ... syndrome Psychiatric Disease ... #generalized #dermatology
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Primary Biliary ... female-predominant disease ... of autoimmune disease ... Cholestasis #PBC #Primary ... #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Most common symptoms ... - Bone symptoms ... - Drugs - Primary ... granulamatous disease ... Diagnosis #Algorithm #hepatology