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differential psychiatry management vasculitis hematology oncology behavioraldisorder inhibitors msk neurology pharmacology serotonin sideeffects adhd allergy als alzheimersdisease amyotrophic anaphylaxis attentiondeficithyperactivedisorder
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... Neutrophils • Immature/Myeloblasts ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Diagnosis
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects • Serotonin Syndrome: - Autonomic Hyperactivity:
• Serotonin Syndrome ... Dizziness - Nausea ... Serotonin #Inhibitors #Pathophysiology ... SideEffects #Psychiatry #Diagnosis ... #Signs #Symptoms
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis ... #signs #symptoms
Fat Embolism Syndrome Trauma to the long bone or pelvis accounts for —9096 of cases. The diagnosis
Fat Embolism Syndrome ... accounts for —9096 of cases ... Pathophysiology ... #Diagnosis #Signs ... #Symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting Serotonin Syndrome - Potentially Life
Vomiting Serotonin Syndrome ... gain Incr NE: Nausea ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... SideEffects #Psychiatry #Diagnosis ... #Signs #Symptoms
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Causes: • Large ... lumbar spine Signs ... #MSK #pathophysiology ... #diagnosis #symptoms ... #signs
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... • Richter’s Syndrome ... • Sezary syndrome ... #diagnosis #workup
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... : • Pathophysiology ... #TLS #diagnosis
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
commonly hairy-cell leukemia ... Viral replication causes ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
Clinical manifestations of anaphylaxis. Neurological (<15%): Dizziness, syncope, seizures, Confusion, impending doom. headache Angioedema: Lips, tongue, orbit,
arrest, Kounis syndrome ... arrest GI (>40%): Nausea ... #anaphylaxis #signs ... #symptoms #diagnosis ... #criteria #allergy
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