13 results
Step by Step Algorithmic Approach to Pediatric Fever

Age < 21 days old (or 28 days for
sensitivity) Leukocytes ... in the urine Procalcitonin ... Peds #Diagnosis #Management
Lower Urinary Tract Infection: Pathogenesis and Clinical Findings

- Predisposing Factors:  Immunocompromised state, diabetes, elderly, female
urethra), stagnant urine ... systems, or stagnant urine ... Tenderness - Urine ... (+) Nitrites, Leukocyte ... UrinaryTractInfection #LUTI #Pathophysiology
Gout: Pathogenesis and Clinical Findings
 - Conditions of rapid cell turnover: hemolysis, psoriasis, lymphoproliferative disorders
 -
for excretion in urine ... cascade results in leukocyte ... Hyperuricemia #Pathophysiology
“Step by Step” – the new kid on the block – aims to risk stratify this
>21 days - No leukocytes ... in urine - Procalcitonin ... #Diagnosis #Management
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
peripheral blood leukocytes ... on the left Myeloblast ... CBC #hematology #pathophysiology
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
The last step in purine ... Homeostasis #Gout #Pathophysiology ... #Medications #Management
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Diagnosis and Management ... Dermatomyositis) AKI - Pathophysiology ... hour with goal urine ... Differential #Diagnosis #Management
Emphysematous Cystitis
Epidemiology:
 • Usually middle-aged diabetic women
 • Other RF: neurogenic bladder, urinary tract outlet obstruction,
Pathophysiology: ... present • UA and Urine ... also important Management ... Cystitis #diagnosis #management
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Product Types: • Leukocyte ... flank pain, dark urine ... proteins on plts, leukocytes ... Transfusions #diagnosis #management
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
flank pain, dark urine ... proteins on plts, leukocytes ... Transfusion #diagnosis #management