25 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
• Blasts > 10% leukocytes ... Neutrophils • Immature/Myeloblasts ... develop leukostasis syndrome ... AML Dx: • ↑ Leukocyte ... • Tumor lysis syndrome
Purple Urine Bag Syndrome
Chronic, indwelling catheter + bacteriuria (Providencia, Klebsiella, E.coli*) + alkaline urine
Tryptophan → Indoxyl
Purple Urine Bag ... Syndrome Chronic ... E.coli*) + alkaline urine ... #Bag #Syndrome ... pathophysiology #clinical
Lower Urinary Tract Infection: Pathogenesis and Clinical Findings

- Predisposing Factors:  Immunocompromised state, diabetes, elderly, female
Pathogenesis and Clinical ... urethra), stagnant urine ... systems, or stagnant urine ... Tenderness - Urine ... (+) Nitrites, Leukocyte
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
differential, urine ... dipstick, urine ... investigations depending on clinical ... Abdominal compartment syndrome ... • Cardio-renal syndrome
Gout: Pathogenesis and Clinical Findings
 - Conditions of rapid cell turnover: hemolysis, psoriasis, lymphoproliferative disorders
 -
Pathogenesis and Clinical ... for excretion in urine ... cascade results in leukocyte
Urine Microscopy - Urinary Sediment Examination Instructions
Preparation of the urine for microscopic examination:
 • Clean catch
Urine Microscopy ... Preparation of the urine ... request fresh urine ... protein, blood or leukocyte ... esterase • Fill conical
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... peripheral blood leukocytes ... on the left Myeloblast ... likelihood of negative clinical
Glitter cells on Urine Microscopy
Leukocytes that phagocytized the Bilirubin crystal!!!

Dr. Telma Lemos @TELMALEMOS10

#GlitterCells #Urine #Microscopy #clinical
Glitter cells on Urine ... Microscopy Leukocytes ... #GlitterCells #Urine ... #Microscopy #clinical
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Compartment syndrome ... Dermatomyositis Clinical ... Weakness - Dark urine ... or compartment syndrome ... hour with goal urine
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... uric acid, LDH, Urine ... Treatment of Clinical ... #Tumor #Lysis #Syndrome