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diagnosis hematology algorithm bruising management purpura workup anemia bleeding blood nonpalpable oncology palpable product reactions aggregometry classification comparison defects destruction
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
, Large platelets ... without platelet ... MYH9-Related Disorder ... comparison #table #differential ... #diagnosis #hematology
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Thrombocytosis - Differential ... Diagnosis Platelet ... Myelofibrosis • Chronic Myeloid ... #Diagnosis #causes ... #Platelets #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... and Platelet Disorders ... History: - Prior platelet ... ITP, unexplained pancytopenia ... #Platelet #Disorders
Platelet disorders and Aggregometry Glanzmann Thrombasthenia • Defective aggregation to all agonists except ristocetin • Normal platelet,
Platelet disorders ... 1 or Type 3) — differentiate ... Gplb receptor • Thrombcytopenia ... #disorders #hematology ... #hemepath #differential
Causes of Thrombocytopenia. Platelet counts may be depressed because of decreased production or due to increased platelet
Causes of Thrombocytopenia ... Platelet counts ... due to increased platelet ... #Diagnosis #Hematology ... #Differential #
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 Thrombocytopenia - Differential Diagnosis Algorithm Decreased production: • Bone marrow suppression • Bone marrow failure • Bone
Thrombocytopenia ... - Differential ... Connective tissue disorders ... #Differential # ... #platelets
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... / Bruising - Differential ... Diagnosis Algorithm Thrombocytopenia ... Platelet Function ... #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... RBC's secondary to platelet ... • Platelet defects ... PURPURA: Platelet ... : - Thrombocytopenia
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
in Children Platelet ... - Increased platelet ... Hypersplenism - Impaired platelet ... Drug-induced Platelet ... count normal - Platelet
Causes of Purpura - Differential Diagnosis Disruption in Vascular Integrity: • Trauma, Infection, Vasculitis, Drug induced
Causes of Purpura ... - Differential ... collagen vascular disorders ... Primary hemostasis: Thrombocytopenia ... , Platelet dysfunction
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