13 results
Causes of Purpura - Differential Diagnosis
Disruption in Vascular Integrity: 
 • Trauma, Infection, Vasculitis, Drug induced
- Differential ... Diagnosis Disruption ... collagen vascular disorders ... Thrombocytopenia, Platelet ... #nonpalpable #palpable
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... Diagnosis #hematology ... rheumatology #palpable #nonpalpable ... #dermatology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Diagnosis Algorithm ... , Auer rod • Lymphoid ... #hematology #Markers ... #Differential #
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... and Management ... (e.g. lymphoma, ... multiple myeloma ... #hematology #differential
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Petechiae/Purpura ... vasculitis) or disorders ... #Dermatology #Rash ... Palpable #Algorithm #Differential ... #Ddxof
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... Diagnosis Algorithm ... Thrombocytopenia - Abnormal platelet ... Vasculitis - Collagen disorders ... #Causes #dermatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
thrombocytopenic purpura ... e.g. lupus, CLL, lymphoma ... lymphoproliferative disorders ... Extravascular #Causes #differential ... #diagnosis #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... - Low Hb and platelets ... Immunohistochemical studies (to differentiate ... #diagnosis #classification ... #management
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Unstable hemoglobin disorders ... , Multiple myeloma ... , Multiple myeloma ... RBC #Morphology #differential ... #diagnosis #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
or lymphoid malignancy ... - Monoclonal - Lymphoid ... younger pts) Differential ... significance (MGUS), CLL, Myeloma ... hemolytic #anemia #hematology