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hematology monoclonal myelodysplastic syndrome agglutinin anemia cell cold disease gammopathy hemolytic leukemia management manifestations mds mgus myelodysplasia paraproteinemias plasmacytoma significance
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... myelodysplastic syndrome • Myeloid ... myelodysplastic #syndrome #differential ... #diagnosis #dermatology ... #oncology #clinical
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Acquired von Willebrand ... lymphoma, multiple myeloma ... assist device (LVAD ... #Management #treatment ... #hematology #differential
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Significance (MGUS) - Differential ... nemaline myopathy Cutaneous-centered ... #Diagnosis #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Myeloid Leukemia ... activity • ↓ LAP ... violaceous, nontender cutaneous ... #Leukemia #Hematology ... #Oncology #Diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
gangrenosum • Cutaneous ... POEMS (Sclerotic myeloma ... angioedema • vWD • acquired ... #Monoclonal #Differential ... #Diagnosis #Oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... presentation) • Cutaneous ... younger pts) Differential ... significance (MGUS), CLL, Myeloma ... hemolytic #anemia #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
, or all three myeloid ... Marrow Failure • Chronic ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
plasmacytoma) Clinical ... Bone marrow Treatment ... • Multiple myeloma ... #Plasmacytoma #Oncology ... #Hematology
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