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diagnosis anemia hemolytic skin monoclonal myelodysplastic algorithm causes crystallina cutaneous disease extravascular gammopathy hemolysis henoch hsp iga intravascular manifestations mds
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin ... Cold Agglutinins ... significance (MGUS ... ), CLL, Myeloma ... hemolytic #anemia #hematology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... ) - Differential ... #Differential # ... Diagnosis #hematology ... #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• MM • WM • MGUS ... anemia due to cold ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
myelodysplastic syndrome • Myeloid ... myelodysplastic #syndrome #differential ... #diagnosis #dermatology ... #oncology #clinical
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... nucleotidase deficiency, lead ... Agglutination - Cold ... agglutinins disease ... Algorithm #workup #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Autoimmune (AIHA)"Cold ... (e.g. primary cold ... agglutin disease ... Extravascular #Causes #differential ... #diagnosis #hematology
Palpable Purpura seen in Henoch Schonlein Purpura (HSP, IgA Vasculitis) 55 year old male on tuberculosis treatment
Vasculitis) 55 year old ... Had sore throat ... IgA #Vasculitis #clinical ... #photo #dermatology ... #skin #rash #physicalexam
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
, or all three myeloid ... compounds, alcohol, lead ... blood count with differential ... Syndromes #diagnosis #hematology ... #oncology
Miliaria Crystallina on Skin Physical Examination A 55-year-old man who had been admitted to the intensive care
Examination A 55-year-old ... man who had been ... Crystallina #Skin #PhysicalExam ... #clinical #video ... #dermatology
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