9 results
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS ... ) - Differential ... #Differential # ... Diagnosis #hematology ... #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... POEMS (Sclerotic myeloma ... anemia due to cold ... #Monoclonal #Differential ... #Diagnosis #Oncology
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
myelodysplastic syndrome • Myeloid ... myelodysplastic #syndrome #differential ... #diagnosis #dermatology ... #oncology #clinical ... #skin
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
(CAD) 2. ... younger pts) Differential ... significance (MGUS ... ), CLL, Myeloma ... hemolytic #anemia #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
CML (Chronic Myeloid ... activity • ↓ LAP ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
Palpable Purpura seen in Henoch Schonlein Purpura (HSP, IgA Vasculitis)

55 year old male on tuberculosis treatment
Vasculitis) 55 year old ... Had sore throat ... clinical #photo #dermatology ... #skin #rash #physicalexam
Miliaria Crystallina on Skin Physical Examination

A 55-year-old man who had been admitted to the intensive care
Crystallina on Skin ... Examination A 55-year-old ... man who had been ... #PhysicalExam # ... clinical #video #dermatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... , or all three myeloid ... compounds, alcohol, lead ... blood count with differential ... #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Gammopathy Include: • MGUS ... • Multiple myeloma ... Smoldering multiple myeloma ... gammopathy, and skin ... Gap #ProteinGap #differential