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diagnosis rheumatology vasculitis cryoglobulins dermpath granulomatosis hematology lesions lupus monoclonal mycobacteria myelodysplastic nontuberculous ntm paraproteinemias pathology polyangiitis semiology signs sle
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... • Myeloid hemopathy ... Infectious manifestations ... diagnosis #dermatology ... #oncology #clinical
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... vasculitis (5%): PAN > GPA ... Vasculitis #dermpath #dermatology ... lesions #diagnosis #clinical ... #manifestations
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... Rarely dominate the clinical ... vasculitis #Dermatologic ... #dermatology #rash
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... associated vasculitis - GPA ... Henoch-Schönlein purpura) • Cutaneous ... systemic lupus erythematosus ... diagnosis #types #classification
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... Manifestations: ... gangrenosum • Cutaneous ... #Monoclonal #Differential ... #Diagnosis #Oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
> PR3 60% • GPA ... tract, and often causes ... mucositis - Rash ... to exclude are infections ... #rheumatology #classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... Disease Classification ... permanent alopecia Differential ... fibromyalgia) • Infections
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
: Erythematous nodules ... , mucositis • Rash ... MPO > PR3 60/ GPA ... tract, and often causes ... / ANCA + MPO) Cryoglobulinemic
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... : • Syndrome of ... Manifestations: ... #differential # ... diagnosis #infectiousdiseases
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