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hematology monoclonal clinical gammopathy mgus myelodysplastic agglutinin allergy alopecia anemia cold cutaneous disease gap globulin hair hairloss hemolytic immunology leukemia
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
myelodysplastic syndrome • Myeloid ... disease course • Significant ... myelodysplastic #syndrome #differential ... #diagnosis #dermatology ... #oncology #clinical
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical Significance ... (MGUS) - Differential ... #MGUS #Differential ... #Diagnosis #hematology ... #oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
of Undetermined Significance ... Hematologic disorder ... #Undetermined #Significance ... #hematology #diagnosis ... #oncology
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Allopecia - Differential ... Diagnosis Framework ... Capitis - Skin ... stress • Significant ... #Diagnosis #dermatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoproliferative disorder ... younger pts) Differential ... of undetermined significance ... (MGUS), CLL, Myeloma ... hemolytic #anemia #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
• Auer Rods Significant ... translocation • Significant ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... POEMS (Sclerotic myeloma ... POEMS (Sclerotic myeloma ... #Monoclonal #Differential ... #Diagnosis #Oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... , or all three myeloid ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Pathergy Summary Overview What is pathergy? Pathergy is an exaggerated skin injury occurring after minor trauma such as
syndrome • Chronic myeloid ... Myeloproliferative disorders ... #Pathergy #diagnosis ... #differential # ... allergy #immunology #dermatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
MGUS • Multiple myeloma ... gammopathy, and skin ... Connective tissue disorders ... Gap #ProteinGap #differential ... #diagnosis #hematology
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