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hematology algorithm hemolytic oncology atlas causes blood bloodcell classification cold disease elevatedmcv extravascular globulin hemolysis hodgkins intravascular key lymphoma macrocytic
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC) Morphology ... Microcytic RBC: ... hemoglobin disorders ... #Morphology #differential ... #diagnosis #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
RBC) Morphology ... Atlas • Microcytic ... #key #diagnosis ... #differential # ... hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Diagnosis Algorithm ... - Abnormal morphology ... anemia - ... bcr-able (+) ↑ WBC ... #hematology #Markers
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... other reproducible morphologic ... Agglutination - Cold agglutinins ... membrane disorder ... #workup #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Diagnosis Algorithm ... • Small Bowel Disorder ... Formation • Multiple Myeloma ... Macrocytosis, Target Cells ... #Causes #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... malignancies - B-cell ... younger pts) Differential ... , Myeloma • Waldenström ... #hematology #diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
. primary cold agglutin ... lymphoproliferative disorders ... • Intrinsic RBC ... G6PD deficiency) ... #diagnosis #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... , or all three myeloid ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Connective tissue disorders ... anemia • Other ... #ProteinGap #differential ... #diagnosis #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Hodgkin Lymphoma - Clinical ... Weight loss • Anemia ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate
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