11 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... (Chronic Myeloid ... (myeloid)↑ • Mature ... Myeloid Leukemia ... #Hematology #Oncology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
the total white blood ... Disorders: • Chronic myeloid ... leukemia (CML) ... myeloid leukemia ... #hematology #basophils
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Thrombocytosis): • Acute ... iron deficiency, hemolysis ... MF) • Chronic myeloid ... leukemia (CML) ... #hematology #secondary
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Diagnosis: • hemolytic ... younger pts) Differential ... Diagnosis Monoclonal ... , Myeloma • Waldenström ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
- Summary Cancer ... cells can indicate disease ... Lymphocytosis: Absolute blood ... ’s lymphoma or acute ... #oncology #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
Chronic kidney disease ... Index > 3: • Acute ... Production #Index #hematology ... #anemia #differential ... #diagnosis #calculation
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
et diutinum Neurologic ... • Coombs (-) hemolytic ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
leukemia • Solitary ... ovarian tumors, lung cancers ... gastric tumors • Hematology ... Gap #ProteinGap #differential ... #diagnosis #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
three myeloid hematopoiesis ... Myeloproliferative Disease ... count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
nodosum • Immune hemolytic ... Immunohistochemical studies (to differentiate ... number of sites of disease ... classification #hematology ... #oncology #management