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hematology neurology shock oncology overview rheumatology syndrome syndromes treatment vasculitis algorithm basophilia basophils cardiology chagas chronic common cvid disease fatigue
Etiologies of Peripheral Neuropathy • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism • Medication-induced: ART, Antibiotics,
Chemotherapy • Infectious ... disease, Leprosy • Inflammatory ... CIDP, Guillain-Barre ... Peripheral #Neuropathy #differential ... #diagnosis #causes
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Diagnosis Framework ... Disorders: • Chronic myeloid ... translocation • Acute myeloid ... Hypersensitivity Or Inflammatory ... #Diagnosis #causes
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
- Differential ... Thrombocytosis): • Acute infection ... hemorrhage) • Chronic inflammatory ... MF) • Chronic myeloid ... #Diagnosis #Causes
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... • Immune response ... directed towards the myelin ... #management #neurology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... • Malignancy Infectious ... Tuberculosis • Epstein-Barr ... Autoimmune / Inflammatory ... Chronic Obstructive Pulmonary
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... Diagnosis Framework ... disorder (Cardiac, pulmonary ... : Myeloma/amyloid ... Polymyositis • Immune
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Gastrointestinal inflammatory ... (specifically immune ... DDX - Other causes ... (Epstein-Barr syndrome ... #management
Causes of Myocarditis 1. Infectious Myocarditis • Bacterial - Staphylococcus, Streptococcus, Pneumococcus, Meningococcus, Gonococcus, Salmonella, Corynebacterium
virus-6, Epstein-Barr ... Immune-mediated ... Kawasaki's disease, inflammatory ... #differential # ... diagnosis #cardiology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Overview Focal inflammatory ... activation of an immune ... vaccination - Myelin ... #management #neurology ... #differential
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
Reconstitution Inflammatory ... neurological symptoms • Caused ... by immune mechanisms ... #Tuberculosis #diagnosis ... #differential #
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