7 results
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Monoclonal Gammopathy ... (MGUS) - Differential ... #Gammopathy #Clinical ... Diagnosis #hematology ... #oncology
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
(IgG type, M- protein ... whom there are no clinical ... concerning for myeloma ... #monoclonal #gammopathy ... #management #hematology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Monoclonal Gammopathy ... No evidence of anemia ... #Monoclonal #Gammopathy ... #Significance #hematology ... #diagnosis #oncology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Syndrome (CAS): ... Viral Infection Clinical ... significance (MGUS ... ), CLL, Myeloma ... #hematology #diagnosis
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Protein/M Component ... et diutinum Neurologic ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Multiple Myeloma ... 40 ml/min A - Anemia ... #Gammopathies #MGUS ... #diagnosis #hematology ... #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
: • MGUS • Multiple ... changes (POEMS syndrome ... gastric tumors • Hematology ... Gap #ProteinGap #differential ... #diagnosis #hematology