31 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... pathophysiology #geriatrics ... #diagnosis #signs ... #symptoms
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
papilledema • Horner syndrome ... • Meningeal signs ... ) • Systemic symptoms ... and signs (e.g. ... Diagnosis #Algorithm #neurology
Causes of Peripheral and Central Vertigo
PERIPHERAL VERTIGO
1. Benign paroxysmal positional vertigo (BPPV) - Short-lived (typically less
Causes of Peripheral ... (Wallenberg's syndrome ... Syndrome usually ... varying neurologic signs ... differential #diagnosis #neurology
Post-Concussive Syndrome
Thinking/Remembering 
 • Difficulty thinking clearly 
 • Feeling slowed down 
 • Difficulty concentrating
Post-Concussive Syndrome ... Physical: • Headache ... • Nausea/vomiting ... #Concussion #Neurology ... #Diagnosis #Symptoms
Clinical manifestations of anaphylaxis. 
Neurological (<15%): Dizziness, syncope, seizures, Confusion, impending doom. headache
Angioedema: Lips, tongue, orbit,
impending doom. headache ... arrest, Kounis syndrome ... arrest GI (>40%): Nausea ... #anaphylaxis #signs ... #symptoms #diagnosis
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
osmolarity If cause ... clinical context and signs ... myoglobin • Myeloma ... Differential #Diagnosis #nephrology ... #causes
13 Dangerous Causes of Headache:
 - subarachnoid hemorrhage: family history, PCKD, known berry aneurysm, sudden and
13 Dangerous Causes ... of Headache: ... shoulder girdle symptoms ... thrombophilia, neurologic signs ... distribution, eyelid
Horner's Syndrome on Physical Exam

A 75yoF was referred in for facial swelling and eyelid changes 1
facial swelling and eyelid ... experience, the cause ... The video highlights ... #clinical #video ... #physicalexam #neurology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... Pressure: • Headache ... Carpal Tunnel Syndrome ... Overproduction #diagnosis #signs ... #symptoms #endocrinology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
CML (Chronic Myeloid ... -> AML: Blast crises ... Blast Phase: • Headaches ... develop leukostasis syndrome ... • Tumor lysis syndrome