15 results
Multiple Myeloma - Treatment Algorithm
a) Newly Diagnosed Myeloma: Transplant Eligible
b) Newly Diagnosed Myeloma: Transplant Ineligible

doi: 10.1038/s41408-020-00359-2

#Multiple
Multiple Myeloma ... Algorithm a) Newly Diagnosed ... -020-00359-2 #Multiple ... #Algorithm #management ... #hematology #oncology
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Multiple Myeloma ... Diagnosis and Management ... osteolytic lesions and pathologic ... #Myeloma #Diagnosis ... #Management #oncology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... and Management ... e.g. lymphoma, multiple ... myeloma, Waldenstrom ... #hematology #differential
Indications for Serum Protein Electrophoresis (SPEP)
 • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
• Suspected multiple ... myeloma, Waldenström's ... • Unexplained pathologic ... Electrophoresis #SPEP #Hematology ... #Diagnosis
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
- Differential Diagnosis ... • Mononeuritis multiplex ... Inflammatory: Myeloma ... #Differential #Diagnosis ... #neurology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Multiple Myeloma ... g/dl LLN B - Bony ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
amyotrophy with the pathologic ... brainstem and multiple ... Can involve any body ... Lateral #Sclerosis #neurology ... #diagnosis #management
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... in literature (NEJM ... cases (Cornelia NEJM ... them, but urgent rheumatology ... #Management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
inflammation of multiple ... skin injury) • Neurologic ... ) Differential Diagnosis ... #management #signs ... #symptoms #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... (to support a diagnosis ... electrophoresis (to exclude multiple ... myeloma) • ANA ... laboratory #workup #diagnosis