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diagnosis oncology clinical differential microscopy monoclonal smear gammopathy management algorithm rheumatology causes multiplemyeloma arthritis body disease formation hemolytic leukemia mds
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... No evidence of anemia ... to IgM multiple myeloma ... insufficiency, Anemia ... to light-chain myeloma
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
vasculitis • Hematologic ... Abnormalities: macrocytic anemia ... criteria for 1) hematologic ... peripheral blood myeloid ... cells NEJM Review
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
significance (MGUS ... 1.5 gm/dL) IgM MGUS ... , low-risk MGUS ... concerning for myeloma ... diagnosis #management #hematology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS ... Features: POEMS, AL amyloid ... deposits: Ig-related amyloid ... #Significance #MGUS ... Differential #Diagnosis #hematology
Rouleaux formation is common in IgM gammopathy and may be particularly striking Genevieve Crane, MD, PhD@evemariecrane #Rouleaux #formation
IgM #gammopathy #MGUS ... #Clinical #Pathology ... #Hematology #Smear
Hypersegmented neutrophil in a case of acute myeloid leukemia. Dysplastic neutrophils are typically hypolobated but can be
case of acute myeloid ... AML #Clinical #Hematology ... #Pathology #Smear
Sickle cell anemia and Howell Jolly bodies (nuclear remnants). - Dr. Abubaker Elshaikh @ElshaikhMD #SickleCell #HowellJolly #Body #Bodies
Sickle cell anemia ... #Body #Bodies #Pathology ... #Hematology #Smear
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• MM • WM • MGUS ... POEMS (Sclerotic myeloma ... POEMS (Sclerotic myeloma ... (-) hemolytic anemia ... Paraproteinemias #Hematology
Diagnosis of active multiple myeloma is not just CRAB; it's actually "SLiM CRAB" @Majorajay & @Vincentrk #MultipleMyeloma
active multiple myeloma ... Oncology #HemeOnc #Hematology ... Hypercalcemia #Anemia
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Reactive: • Anemia ... Myelofibrosis • Chronic Myeloid ... causes #Platelets #hematology
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