8 results
diagnosis oncology gammopathy multiplemyeloma agglutinin algorithm cell clinical cold disease gammopathies gap globulin hemolytic management paraproteinemias plasmacytoma proteingap solitary undetermined
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
of undetermined significance ... (IgG type, M- protein ... concerning for myeloma ... #MGUS #Biopsy # ... diagnosis #management #hematology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
of Clinical Significance ... (MGUS) - Differential ... Gammopathy #Clinical #Significance ... #MGUS #Differential ... #Diagnosis #hematology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
of Undetermined Significance ... protein level <3 ... No evidence of anemia ... insufficiency, Anemia ... #Undetermined #Significance
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Protein/M Component ... • MM • WM • MGUS ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Multiple Myeloma ... 40 ml/min A - Anemia ... gamma gap (total protein ... #Gammopathies #MGUS ... #diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... younger pts) Differential ... of undetermined significance ... (MGUS), CLL, Myeloma ... #hematology #diagnosis
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Gammopathy Include: • MGUS ... • Multiple myeloma ... Smoldering multiple myeloma ... Thalassemia, Sickle cell anemia ... Gap #ProteinGap #differential
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
tissue composed of monoclonal ... • No CRAB - no anemia ... IFE, FLC assay Pathology ... • Multiple myeloma ... Diagnosis #Workup #Hematology
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