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diagnosis oncology clinical differential monoclonal smear gammopathy management algorithm microscopy causes multiplemyeloma arthritis disease formation hemolytic leukemia mds myelodysplastic plasmacell
Sickle cell anemia and Howell Jolly bodies (nuclear remnants). - Dr. Abubaker Elshaikh @ElshaikhMD #SickleCell #HowellJolly #Body #Bodies
Sickle cell anemia ... #HowellJolly #Body ... #Bodies #Pathology ... #Hematology #Smear
Rouleaux formation is common in IgM gammopathy and may be particularly striking Genevieve Crane, MD, PhD@evemariecrane #Rouleaux #formation
IgM #gammopathy #MGUS ... #Clinical #Pathology ... #Hematology #Smear
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Reactive: • Anemia ... Non-infectious (malignancy, rheumatologic ... Myelofibrosis • Chronic Myeloid ... causes #Platelets #hematology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
vasculitis • Hematologic ... Abnormalities: macrocytic anemia ... criteria for 1) hematologic ... cells NEJM Review ... Autoinflammatory #Somatic #rheumatology
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
significance (MGUS ... 1.5 gm/dL) IgM MGUS ... , low-risk MGUS ... concerning for myeloma ... diagnosis #management #hematology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS ... Features: POEMS, AL amyloid ... deposits: Ig-related amyloid ... #Significance #MGUS ... Differential #Diagnosis #hematology
Hypersegmented neutrophil in a case of acute myeloid leukemia. Dysplastic neutrophils are typically hypolobated but can be
case of acute myeloid ... AML #Clinical #Hematology ... #Pathology #Smear
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... No evidence of anemia ... to IgM multiple myeloma ... insufficiency, Anemia ... #Significance #hematology
Diagnosis of active multiple myeloma is not just CRAB; it's actually "SLiM CRAB" @Majorajay & @Vincentrk #MultipleMyeloma
active multiple myeloma ... Oncology #HemeOnc #Hematology ... Hypercalcemia #Anemia
Leukoerythroblastosis and myelophthisic anemia can be associated with any marrow-replacing process. In this case, the likely
myelophthisic anemia ... Leukoerythroblastosis #Hematology ... #Pathology #Smear
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