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clinical microscopy ct honc myeloma smear arm autoinflammatory body bonemarrow cd138 cilnical cutismarmorata decompressionsickness diagnosis e1 em extramedullaryhematopoiesis eyelid formation
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
vasculitis • Hematologic ... criteria for 1) hematologic ... (12%) • giant cell ... hematopoietic stem cells ... cells NEJM Review
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Plasma cell leukemia ... other forms of myeloma ... primary plasma cell ... Clinical #Smear #Hematology ... #Pathology
Eyelid Melanoma - Despite conservative interventions, the stye had persisted and the skin had become noticeably
Eyelid Melanoma ... the left upper eyelid ... C) #Clinical #Pathology ... #Derm #Eyelid # ... Melanoma #Microscopy #NEJM
Decompression Sickness - The physical examination revealed diffuse violaceous skin mottling over his trunk and arms
and vomiting as well ... #Clinical #Derm ... #EM #Radiology # ... Pneumatosis #CT #NEJM
Myeloma: In this BM core, most plasma cells contain cytoplasmic immunoglobulin (Russell bodies). They're difficult to identify
Myeloma: In this ... core, most plasma cells ... #Myeloma #CD138 ... BoneMarrow #Clinical #Pathology ... #Hematology
Glucagonoma-Associated Rash - The rash involved the arms, genitals, and buttocks and had progressed to the
tissue revealed a well-circumscribed ... Clinical #HONC #Derm ... #Pathology #Radiology ... Microscopy #CT #NEJM
Perirenal Extramedullary Hematopoiesis - Magnetic resonance imaging of the abdomen, performed without the administration of contrast
erythroid and myeloid ... hematopoiesis #cilnical #Radiology ... #Pathology #Honc ... ExtramedullaryHematopoiesis #Microscopy #NEJM
Grouped Pustules on an Erythematous Base - On physical examination, grouped, coalescing pustules that had scalloped
multinucleated giant cells ... #Clinical #Derm ... #Pathology #Herpes ... Smear #Microscopy #NEJM
Raindrop Skull- ...A skeletal survey showed diffuse osteopenia, a pubic bone fracture, and numerous radiolucent lesions
characteristic of multiple myeloma ... clonal plasma cells ... #NEJM #clinical ... #radiology #skull ... raindrop #multiple #myeloma
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Solitary Cell Plasmacytoma ... patients with EMD myeloma ... IFE, FLC assay Pathology ... • Multiple myeloma ... Diagnosis #Workup #Hematology
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