15 results
diagnosis differential causes cll lymphocytic management mds monoclonal myelodysplastic systemic agglutinin autoinflammatory cancer cold dermatology e1 elevatedmcv erythematosus gammopathies gap
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
thromboembolic disease ... vasculitis • Hematologic ... Abnormalities: macrocytic anemia ... cells NEJM Review ... Autoinflammatory #Somatic #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... extramedullary disease ... Myeloid Leukemia ... - infiltrates (anemia ... #Hematology #Oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... POEMS (Sclerotic myeloma ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Multiple Myeloma ... 40 ml/min A - Anemia ... #Gammopathies #MGUS ... #diagnosis #hematology ... #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Management Summary myelo ... cytopenias (usually anemia ... transformation to acute leukemia ... Management #treatment #hematology ... #oncology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Kawasaki, Nephrotic syndrome ... • Infections: Chronic ... #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Differential Diagnosis Algorithm ... Formation • Multiple Myeloma ... Myelodysplastic Syndromes ... • Rule out B12 and ... #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... cells can indicate disease ... • Neutropenia, anemia ... diagnosis #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... 5) Symptoms of anemia ... chemotherapy for low-risk disease ... lymphadenopathy and ... #oncology #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
- Systemic and ... Creatinine & BUN: • Chronic ... renal failure/uremia ... • Lymphoma • Leukemia ... Myelodisplastic syndrome
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