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diagnosis differential rheumatology hepatology leukemia liver management amyloid amyloidosis atlas autoinflammatory beaus cancer common cvid diseases e1 enzymes erythematosus fingernails
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... (Chronic Myeloid ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... : • Common Clinical ... thromboembolic disease ... (12%) • giant cell ... cells NEJM Review
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... cells can indicate disease ... diagnosis #workup #oncology ... #hematology
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Management Summary Clinical ... Signs: • hyperCalcemia ... demineralization) • Renal disease ... osteolytic lesions and pathologic ... Diagnosis #Management #oncology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... vein: Budd-chiari syndrome ... lymphoma, melanoma, myeloma ... > 2 • NASH, Chronic ... #hepatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
three myeloid hematopoiesis ... Marrow Failure • Chronic ... Myeloproliferative Disease ... #diagnosis #hematology ... #oncology
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Clinical suspicion ... the extent of disease ... Amyloidosis Clinical ... : • Nephrotic syndrome ... Carpal tunnel syndrome
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
tests algorithm ... symptoms/signs ... box indicates all ... presence of metabolic syndrome ... #Algorithm #Hepatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... to 8 years Clinical ... Autoimmunity • Chronic ... : • Nephrotic syndrome ... hypogammaglobulinemia #immunology #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Malignancy (e.g. hematologic ... Clinical Features ... vein thrombosis Hematologic ... with Lupus: • Chronic
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