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diagnosis differential agglutinin anemia cold dermatology gammopathy hemolytic management manifestations mgus myelodysplastic paraproteinemias rheumatology significance skin symptoms
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
of Clinical Significance ... nemaline myopathy Cutaneous-centered ... Ig deposition disease ... Differential #Diagnosis #hematology ... #oncology
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... • Myeloid hemopathy ... appearing during the disease ... Calmettes #Cutaneous ... #oncology #clinical
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... vasculitis) • Cutaneous ... syndrome (Clinical ... : monoclonal TNF-aIpha ... #management #signs
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... gangrenosum • Cutaneous ... POEMS (Sclerotic myeloma ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... presentation) • Cutaneous ... significance (MGUS), CLL, Myeloma ... hemolytic #anemia #hematology
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