23 results
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... : • Common Clinical ... vasculitis • Hematologic ... criteria for 1) hematologic ... cells NEJM Review
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
case of acute myeloid ... neutrophils #AML #Clinical ... #Hematology #Pathology
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
other forms of myeloma ... rouleaux #formation #Clinical ... #Smear #Hematology ... #Pathology
Eyelid Melanoma - Despite conservative interventions, the stye had persisted and the skin had become noticeably
Eyelid Melanoma ... mitogenesis (Panel C) #Clinical ... #Pathology #Derm ... #Eyelid #Melanoma ... #Microscopy #NEJM
Nail Findings & Associated Conditions
Change in color, texture, or shape can be harmless, but may suggest
• Green Nail Syndrome ... • Yellow Nail Syndrome ... Nail #fingernail #pathology ... differential #diagnosis #dermatology ... #nails #table #
Nail Findings & Associated Conditions
Change in color, texture, or shape can be harmless, but may suggest
• Green Nail Syndrome ... • Yellow Nail Syndrome ... Nail #fingernail #pathology ... differential #diagnosis #dermatology ... #nails #table #
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
myelodysplastic syndrome ... • Myeloid hemopathy ... myelodysplastic #syndrome ... differential #diagnosis #dermatology ... #oncology #clinical
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... capillary leak syndrome ... • Schnitzler syndrome ... Monoclonal #Gammopathy #Clinical ... Differential #Diagnosis #hematology
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Anti-Synthetase Syndrome ... Antibodies #MSAs #clinical ... #diagnosis #rheumatology ... #table