Myeloid pathology neurology reflex sem glomerulus desposition gbm differential - GrepMed

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This image shows portions of glomerular tuft with collapsed GBM (across top), spicular amyloid (middle right),

#GBM #amyloid # ... desposition #deposits ... ElectronMicroscopy #SEM ... #clinical #nephrology ... #pathology

This image shows glomerular tuft with overall intact architecture. Discrete masses of specular amyloid interrupt smooth

This image shows glomerular ... #amyloid #desposition ... ElectronMicroscopy #SEM ... #clinical #nephrology ... #pathology

This image shows a glomerular tuft with overall intact architecture. Discrete masses of specular amyloid (long

image shows a glomerular ... #amyloid #desposition ... ElectronMicroscopy #SEM ... #clinical #nephrology ... #pathology

Spectrum of Glomerular Diseases
Nephrotic - Mechanism:
• Injury to podocytes
• Changed architecture: Scanning. Deposition of

Spectrum of Glomerular ... Deposition of matrix ... • Breaks in GBM ... #Diseases #differential ... spectrum #diagnosis #nephrology

This image shows acellular scanning EM showing glomerular basement membrane duplication at high power in a

showing glomerular ... high power in a glomerulus ... arkanalabs #GBM ... #clinical #nephrology ... #pathology

Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight

Proteinuria - Differential ... • Multiple Myeloma ... • Drugs Glomerular ... proliferative • Anti-GBM ... #Differential #

Rapidly Progressive Glomerulonephritis (RPGN)
- Loss of kidney function over a short period of tirne

Basement Membrane (GBM ... Linear, ribbon-like GBM ... staining on IF • No EM ... Classification #Differential ... #Diagnosis #Nephrology

This image shows spicular amyloid with tapering conical masses interconnected by branching fibrils!

Dr. Stephen Bonsib via

shows spicular amyloid ... #spicular #desposition ... ElectronMicroscopy #SEM ... #clinical #nephrology ... #pathology

This image shows spicular amyloid deposits showing blunt conical formations with interconnecting fibrils.

Dr. Stephen Bonsib via

shows spicular amyloid ... #deposits #deposition ... ElectronMicroscopy #SEM ... #clinical #nephrology ... #pathology #renal

Stage II Membranous Glomerulonephritis on Electron Microscopy
This eyeSCANdy image shows acellular scanning EM of a glomerulus

of a glomerulus ... appearance of GBM ... ElectronMicroscopy #SEM ... #clinical #nephrology ... #pathology

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