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diagnosis differential management oncology pbc algorithm causes primary thrombocytopenia arterial autoantibodies basophilia basophils cholangitis comparison embolism gap globulin hemeonc heparin
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis #pathophysiology #pbc #psc #hepatology #comparison
Disease: Primary Biliary ... Cirrhosis vs Primary ... Cholangitis #pathophysiology ... #pbc #psc #hepatology
Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
Primary Biliary ... Cirrhosis - Pathophysiology ... #PBC #Primary #Biliary ... #Cirrhosis #Pathophysiology ... #hepatology
Systemic Sclerosis Associated Autoantibodies Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis Anti-centromere: Limited skin disease (~93-95%), Pulmonary
anti-Sc170): Diffuse skin ... ulcers, Primary Biliary ... Cirrhosis Anti-RNA ... Rapid progressive skin ... Autoantibodies #diagnosis #rheumatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Polycythemia • Multiple Myeloma ... Cholangitis • Primary Biliary ... Cirrhosis #Hepatomegaly ... Algorithm #Causes #Hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... Cirrhosis (PBC) ... 65 years PBC Pathophysiology ... Examination: • Skin ... diagnosis #workup #hepatology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Disorders: • Chronic myeloid ... translocation • Acute myeloid ... Irradiation • Cirrhosis ... Diagnosis #causes #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
lymphoma, melanoma, myeloma ... Extrahepatic - Biliary ... - Obstruction: Biliary ... hepatitis: < 1 • Cirrhosis ... diagnosis #algorithm #hepatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
arterial thrombosis, skin ... ♀, ↑Age, ESRD Pathophysiology ... exposure (prevent skin ... Management #Treatment #Hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... POEMS (Sclerotic myeloma ... POEMS (Sclerotic myeloma ... thrombosis+Pulm HTN+skin ... Paraproteinemias #Hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Testosterone - Coumadin skin ... Venous #Arterial #pathophysiology ... #hematology #differential
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