100 results
Myositis and Myopathies
#ESR #CK #Differential diagnosis of myopathy 
#Inflammatory #myopathies	#Dermatomyositis	
#muscle weakness
#Polymyositis	
#Inclusion body myositis
#Polymyalgia rheumatica	
#Fibromyalgia	
#Hypothyroid myopathy	
#Muscle stiffness
#Drug-induced
Differential diagnosis of myopathy ... Fibromyalgia #Hypothyroid ... myopathy #Muscle ... Statin-induced myopathy ... Cocaine-induced myopathy
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
Hypothyroid Myopathy ... Symmetric, proximal myopathy ... Rhabdomyolysis (rare) #Hypothyroid ... #Myopathy #pathophysiology ... #signs #symptoms
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Statin-Associated Muscle Symptoms ... onset of muscle symptoms ... Symptoms: • Proximal ... , hypothyroid-induced ... Muscle biopsy if symptoms
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
Hypothyroidism – symptoms ... Symptoms: Tiredness ... hypertrophy, Proximal myopathy ... reflexes, Anaemia #Hypothyroid ... Features #Signs #Symptoms
Myelopathy - Injury to the entire spinal cord - Signs and Symptoms
 • Ataxia (early sign)
Myelopathy - Injury ... cord - Signs and Symptoms ... early signs) #Myelopathy ... diagnosis #signs #symptoms
Myoedema in Hypothyroidism on Physical Exam

Hypothyroidism is a clinical syndrome resulting from the production, secretion or
varied clinical symptoms ... There are several symptoms ... and scaly skin, myopathy ... Myopathy due to ... endocrinology #hypothyroid
Hypothyroidism and Hyperthyroidism - Symptoms and Signs
Hypothyroidism:
 - General - From asymptomatic to myxedema coma, “Like
Hyperthyroidism - Symptoms ... MSc @AmyChung #Hypothyroid ... #Hyperthyroid # ... Symptoms #Signs
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
Hyperparathyroid - Hyperthyroid ... pathophysiology #signs #symptoms
Causes of Back Pain - Differential Diagnosis Algorithm
Always assess for red flags. If no red flags,
constitutional symptoms ... Unresolved Radicular Symptoms ... Spondyloarthropathies • Myelopathic
Symptoms of Hypophosphatemia
 • CNS: Seizures, Delirium, Paresthesias, Central & extrapontine myelinolysis, Hallucinations, Fatigue
 • Hematologic:
Symptoms of Hypophosphatemia ... MSK: Proximal myopathy ... Hypophosphatemia #Phosphate #Symptoms