60 results
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
of Peripheral Weakness ... Differential Diagnosis Algorithm ... Lambert-Eaton Myasthenic Syndrome ... • Congenital Myopathy ... Differential #Diagnosis #Algorithm
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... level of muscle weakness ... anti-synthetase syndrome ... have significant weakness ... after 2 years of treatment
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
proximal myalgia and weakness ... any time during treatment ... symmetric muscle weakness ... Guillain-Barré syndrome ... antisynthetase syndrome
Causes of Peripheral Weakness - With and Without Sensory Changes - Differential Diagnosis Algorithm
With Sensory Changes:
of Peripheral Weakness ... Differential Diagnosis Algorithm ... • No Objective Weakness ... Oculomotor • Myopathy ... Differential #Diagnosis #Algorithm
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
Myalgia, Muscle weakness ... Psychosis, Deafness ... of movement, Deafness ... Carpal timel syndrome ... hypertrophy, Proximal myopathy
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Guillain-Barre syndrome ... Lambert Eaton Syndrome ... Mitochondrial myopathy ... Neuromuscular #Weakness
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Immune-Mediated Necrotizing Myopathy ... Antisynthetase Syndrome ... Myopathies #Idiopathic #Myopathy ... Comparison #Managment #algorithm
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
• Acute stroke syndromes ... Paraneoplastic syndrome ... Lambert-Eaton - Isaacs' syndrome ... Myopathy: ... mediated necrotizing myopathy
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Miller Fisher Syndrome ... Treatment: • Plasmapheresis ... Guillain #Barre #Syndrome ... diagnosis #management #treatment
Suggested algorithm for treating irritable bowel syndrome-diarrheal type (IBS-D) 

#IBSD #diarrhea #Algorithm #irritable #bowel #syndrome #management
Suggested algorithm ... irritable bowel syndrome-diarrheal ... IBSD #diarrhea #Algorithm ... irritable #bowel #syndrome ... #management #treatment