21 results
Myelopathy - Injury to the entire spinal cord - Signs and Symptoms
 • Ataxia (early sign)
Myelopathy - Injury ... and Symptoms ... • Gross motor weakness ... #diagnosis #signs ... #symptoms #msk
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
and signs. ... Myalgia, Muscle weakness ... Carpal timel syndrome ... hypertrophy, Proximal myopathy ... #Symptoms #Diagnosis
Symptoms of Hypophosphatemia
 • CNS: Seizures, Delirium, Paresthesias, Central & extrapontine myelinolysis, Hallucinations, Fatigue
 • Hematologic:
Symptoms of Hypophosphatemia ... Bone pain • MSK ... : Proximal myopathy ... Diaphragmatic weakness ... #Signs #Diagnosis
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Upper extremity weakness ... #diagnosis #pathophysiology ... #signs #symptoms ... #msk #orthopedics ... #neurology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
80%) - Proximal Weakness ... femoral heads • Myopathy ... Erythematosus #SLE #MSK ... pathophysiology #signs ... #symptoms #diagnosis
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
level of muscle weakness ... less systemic symptoms ... heliotrope rash, Shaw sign ... , holster sign, ... anti-synthetase syndrome
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Demyelinating Disease (MS ... Mitochondrial myopathy ... #differential #diagnosis ... #neurology
NINDS Diagnostic Criteria for Guillain Barre Syndrome 
Features Required for Guillain-Barré Syndrome:
 • Progressive muscle weakness
Progression of weakness ... , Mild sensory symptoms ... or signs, Cranial ... nervous system signs ... #neurology #neuropathy
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
Antalgic gait - Weakness ... TendonRupture #diagnosis ... #signs #symptoms ... pathophysiology #msk ... #orthopedics
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Diagnosis Framework ... • Acute stroke syndromes ... Lack of UMN/LMN signs ... #Differential #Diagnosis ... #neurology