21 results
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
and signs. ... Myalgia, Muscle weakness ... Carpal timel syndrome ... hypertrophy, Proximal myopathy ... #PhysicalExam #
NINDS Diagnostic Criteria for Guillain Barre Syndrome 
Features Required for Guillain-Barré Syndrome:
 • Progressive muscle weakness
Syndrome Features ... Syndrome: • Progressive ... , Mild sensory symptoms ... Miller Fisher syndrome-Bickerstaff ... #Syndrome #diagnosis
Guillain-Barre Syndrome
An acute polyneuropathy (disorder Of the peripheral nervous System).
Symptoms are Often symmetrical and progress Over
Guillain-Barre Syndrome ... Symptoms are Often ... GuillainBarre #Syndrome ... #Diagnosis #Neurology ... #Signs
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
• Spinal Cord: ... Poliomyelitis, Guillain-Barre ... syndrome, Mononeuritis ... Lambert Eaton Syndrome ... differential #diagnosis #neurology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Syndrome -> Anterior ... Syndrome ->Cord ... Syndrome -> Posterior ... Brown-Sequard Syndrome ... #symptoms #msk
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
- Spinal Cord Syndromes ... Brown-Séquard Syndrome ... Syndrome: • Etiology ... Syndrome: • Etiology ... #syndromes #lesions
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
and signs below ... - Radiation myelopathy ... - Radiation myelopathy ... MCTD, Sjogren syndrome ... disorders #diagnosis #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
• Acute stroke syndromes ... of the spinal cord ... Paraneoplastic syndrome ... Lambert-Eaton - Isaacs' syndrome ... Lack of UMN/LMN signs
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
proximal myalgia and weakness ... , Guillain-Barré ... syndrome (GBS), ... antisynthetase syndrome ... Lambert-Eaton myasthenic syndrome
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
level of muscle weakness ... less systemic symptoms ... heliotrope rash, Shaw sign ... , holster sign, ... anti-synthetase syndrome