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LAMP2 cardiomyopathy in a 12-year-old boy with sudden death (Table 1; patient #1). A. At autopsy,
sudden death (Table 1; ... patient #1). ... muscle cells (myocytes ... #Clinical #Gross
CARDIAC MYOCYTE POTENTIALS #Pathophysiology #Cardiology #Cardiac #Myocyte #Ventricular #ActionPotentials #Channels #Phases
CARDIAC MYOCYTE ... Cardiology #Cardiac #Myocyte
Action potential in cardiomyocytes The action potential in typical cardiomyocytes is composed of 5 phases (0-4), beginning
Depolarization Phase 1: ... ActionPotential #Myocytes
Innate Immune Cells - Pathophysiology The innate immune system consists of granulocytes, mast cells, natural killer cells,
killer cells, and monocytes ... Monocytes and neutrophils ... Monocytes and B-cells
Cardiac Myocyte Contractile cycle - Ca2+ binds to TnC → TnI is inhibited → conformational change
Cardiac Myocyte ... Pathophysiology #Cardiology #Myocyte
Characteristics of Selected Pneumonias Streptococcus pneumoniae (pneumococcus). Gram-positive diplococci. Haemophilus influenzae. Pleomorphic gram-negative coccobacilli. Staphylococcus aureus. Plump
PMNs and monocytes
Fever - Pyrogen Pathophysiology EXOGENOUS PYROGEN • Bacteria: Lipopolysaccharide components, peptidoglycans and muramyl peptide derivatives, Toxins •
(neutrophils, monocytes ... pyrogen) TNF, IL-1,
Cardiomyopathies Manifestations of cardiomyopathy (CM) range from microscopic alterations in cardiac myocytes to fulminant Heart Failure
alterations in cardiac myocytes
Rigors And Bacteremia - Overview • Rigors are a response to the release of cytokines and prostaglandins
: Neutrophils, Monocytes ... Pyrogen (TNF, IL-1,
McDonald Criteria for Diagnosis of Multiple Sclerosis • 2 or more attacks, 2 or more lesions
Clinical evidence ... more attacks, 1 ... CNS site) • 1 ... CNS site) • 1 ... attack, 1 lesion
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