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diagnosis clinical differential management algorithm pocus causes ultrasound cardiology treatment peds infectiousdiseases pediatrics signs rheumatology symptoms pulmonary microbiology comparison dermatology
Causes of Fever: IMADE Mnemonic INFECTION • Infection 1.0 - Common & Localizing: Base Rate • Infection
Causes of Fever: ... carcinomas present with fever ... Vasculitides • Myosites ... with DVT/PE + fever ... pheochromocytoma #Fever
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Cardiac: • Myocyte ... myocarditis, rheumatic fever
CARDIAC MYOCYTE POTENTIALS #Pathophysiology #Cardiology #Cardiac #Myocyte #Ventricular #ActionPotentials #Channels #Phases
CARDIAC MYOCYTE ... Cardiology #Cardiac #Myocyte
Faget Sign - Pulse-Temperature Dissociation Causes of Relative Bradycardia • Infectious Causes: Legionella, Psittacosis, Q fever, Typhoid
Psittacosis, Q fever ... , Typhoid fever, ... , Dengue fever, ... Mountain spotted fever ... , Drug fever
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Fever Patterns - ... Continuous Fever ... (Step ladder: fever ... Intermittent Fever ... or no fever •
Fever - Pyrogen Pathophysiology EXOGENOUS PYROGEN • Bacteria: Lipopolysaccharide components, peptidoglycans and muramyl peptide derivatives, Toxins •
Fever - Pyrogen ... (neutrophils, monocytes ... production → Fever ... #Fever #Pathophysiology
Causes of Relative Bradycardia - Note the propensity for intracellular organisms. Infectious: Legionella, Psittacosis, Q fever, Typhoid
Psittacosis, Q fever ... , Typhoid fever, ... , Dengue fever, ... Mountain spotted fever ... , Drug fever
Faget's Sign & Liebermeister's Rule Pulse-Temperature Dissociation EVERY 1 F RISE IN TEMPERATURE -> HR INCREASES 8-10 BPM INFECTIOUS
Psittacosis • Q Fever ... • Typhoid Fever ... • Drug Fever ... Typhoid Fever (S ... Dengue Fever NOTE
Innate Immune Cells - Pathophysiology The innate immune system consists of granulocytes, mast cells, natural killer cells,
killer cells, and monocytes ... Monocytes and neutrophils ... Monocytes and B-cells
Action potential in cardiomyocytes The action potential in typical cardiomyocytes is composed of 5 phases (0-4), beginning
ActionPotential #Myocytes
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